Yes, it is possible mix different media-based building kits on a layout. In fact, it can add a lot of visual interest...
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US Navy LCT Mk 6 - Landing Craft tank 501 class (1943-45)
Knox Class Frigate FF-1073
HMS Fearless 121 parts
Starter Set - Mary Rose 1:400 scale model kit 29 parts
US Navy LST-491 Class WW2 Landing
QUEEN MARY 2 Ocean Liner Ship 1:1200 Model kit. Includes building instructions and decals. Paints, glue or brushes are NOT included.
Sir Francis Drake's flagship "Golden Hind" - 1:350 Kit: 65 parts