Yes, it is possible mix different media-based building kits on a layout. In fact, it can add a lot of visual interest...
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Metropolitan Railway 20t Guards VanResin Model Kit.
LSWR 8 ton Van Rebuilt by the Southern Railway from a 10t Road VanResin Model Kit.
LSWR 20 ton Goods Brake Van (Road Van) S.R. Dia 1545 & 1549Resin Model Kit.
LSWR, SR & BR 18t Road (Brake) Van - Dia 1542
LSWR 10 ton Goods Brake Van (Road Van) S.R. Dia 1541Resin Model Kit.
LBSCR 6/10 ton Cattle Wagon S.R. Dia. 1527 Rebuilt (8)Resin Model Kit.
LBSCR 6/10 ton Cattle Wagon S.R. Dia. 1527 (8)Resin Model Kit.
LBSCR 8 ton Goods Van S.R. Dia. 1434Resin Model Kit.
LBSCR 5 plank Open Goods Waggon S.R. Dia. 1369 SquareResin Model Kit.
LBSCR 5 plank Open Goods Waggon S.R. Dia. 1369 RoundResin Model Kit.
S.R. (LSWR) 10t Rebuilt Goods Brake Van (Road Van).
LBSCR first/third Composite 4 Wheel Stroudley Coach as used on the Isle of Wight between 1923 and 1931/2. Resin Model Kit.